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Allergens per 0.5 mL
Amphotericin B
RabAvert (Novartis)
Rabies
< 2 ng
Calf Lymph
Dryvax (W)
Smallpox
RabAvert (Chiron)
Rabies
Bovine Serum used in cell culture process
Chicken Protein
Afluria (CSL)
Influenza
trace amounts
Fluarix (GSK)
Influenza
trace amounts
FluLaval (GSK) Influenza trace amounts
H1N1 (CSL)
H1N1 Influenza
trace amounts
Imovax (sp)
Rabies
trace amounts
RabAvert (Chiron)
Rabies
trace amounts
YF-Vax (sp)
Yellow Fever
trace amounts
Chlortetracyclin
Dryvax (W)
Smallpox
200 mcg/mL (100/0.5 mL)
RabAvert (Novartis)
Rabies
< 20 ng
Dihydrostreptomycin
Dryvax (W)
Smallpox
200 mcg/mL (100/0.5 mL)
Egg
Afluria (CSL)
Influenza
residual egg proteins
Agriflu (Novartis) Influenza residual, <0.4 mcg Attenuvax (Merck) Measles residual egg proteins
Fluarix (GSK)
Influenza
residual
FluLaval (GSK)
Influenza
residual (≤1 mcg ovalbumin)
Flumist (MedImmune)
Influenza
Fluvirin (Novartis)
Influenza
residual
Fluzone (sp)
Influenza
residual
H1N1 (CSL)
H1N1 Influenza
residual
H1N1 (GSK) H1N1 Influenza ≤1 mcg
H1N1 (Novartis)
H1N1 Influenza
trace amounts
H1N1 (sanofi pasteur)
H1N1 Influenza
trace amounts
H1N1-nasal (MedImmune)
H1N1 Influenza
trace amounts
MMR II (Merck)
MMR
residual
Mumpsvax (Merck)
Mumps
residual
ProQuad (Merck)
MMR+varicella
residual
RabAvert (Chiron)
Rabies
trace amounts
YF-Vax (sp) Yellow Fever trace amounts Gelatin (Bovine)
RabAvert (Novartis)
Rabies
<12 mg (Polygeline)
Attenuvax (Merck)
Measles
Hydrolyzed Gelatin, 14.5 mg
[click here for information from religious leaders on on use of these vaccines]
Flumist (MedImmune) Influenza Hydrolyzed Gelatin, 2.00 mg Fluzone (sp)
Influenza
0.05% (added as a stabilizer)
H1N1 (sanofi pasteur)
H1N1 Influenza
0.05% (added as a stabilizer) H1N1-nasal (MedImmune)
H1N1 Influenza
Hydrolyzed Gelatin, 2.00 mg JE-Vax Japanese Encephalitis <500 mcg Meruvax II (Merck)
Rubella
Hydrolyzed Gelatin, 14.5 mg
MMR II (Merck)
Measles, Mumps, Rubella
Hydrolyzed Gelatin, 11 mg
Mumpsvax (Merck)
Mumps
Hydrolyzed Gelatin, 14.5 mg
ProQuad (Merck)
MMR+varicella
Hydrolyzed Gelatin, 14.5 mg
Tripedia (sp)
DTaP
residual used in the production of the pertussis concentrate
Varivax (Merck)
Varicella
Hydrolyzed Gelatin, 12.5 mg/dose
YF-Vax (sp)
Yellow Fever
as stabilizer
Zostavax (Merck)
Varicella Zoster
Hydrolyzed gelatin, 15.58 mg
Gentamicin Sulfate
Flumist (MedImmune)
Influenza
<0.015 mcg/mL
Fluarix (GSK)
Influenza
≤0.15 mcg
H1N1-nasal (MedImmune)
H1N1 Influenza
<0.015 mcg/mL
Latex
ActHIB (AP)
Hib
Diluent vial stopper; vaccine vial contains no rubber
Boostrix (GSK)
Tdap
Cap/Plunger of needleless prefilled syringe contain dry natural latex rubber
Comvax (Merck)
Hib-HepB
Stopper
DAPTACEL (sp)
DTaP
Stopper
DT (AP)
DT
Stopper
Engerix-B (GSK)
Hep B
Cap/Plunger of needleless prefilled syringe contain dry natural latex rubber
Fluarix (GSK)
Influenza
Cap/Plunger of needleless prefilled syringe contain dry natural latex rubber
Certarix (GSK)
HPV
Tip cap and plunger of needleless prefilled syringes contain dry natural latex rubber; vial stopper is latex-free
Havrix (GSK)
Hep A
Cap/Plunger of needleless prefilled syringe contain dry natural latex rubber
HibTITER (Wyeth)
Hib
vial stopper contains dry natural rubber
Infanrix (GSK)
DTaP
Cap/Plunger of needleless prefilled syringe contain dry natural latex rubber
Kinrix (GSK)
DTaP/IPV
Syringe may contain dry natural latex rubber
Menactra (sp)
Meningococcal
Stopper
MENOMUNE (sp)
Meningococcal
Stopper
Pediarix (GSK)
DTaP-HepB-IPV
Cap/Plunger of needleless prefilled Syringe contain dry natural latex rubber
PedvaxHIB (Merck)
Hib
Prevnar (WL)
Pneumococcal
Stopper
Rotarix (GSK)
Rotaviris
Tip cap and Rubber Plunger of applicator
Td (sp)
Td
Stopper, needle cover, plunger
TriHIBit (sp)
DTaP-Hib
Diluent vial stopper; vaccine vial contains no rubber
Tripedia (sp)
DTaP
Stopper
Twinrix (GSK)
Hep AB
Tip cap and plunger of needleless prefilled syringes contain dry natural latex rubber; vial stopper is latex-free
Vaqta (Merck)
Hepatitis A
Stopper
YF-Vax (sp)
Yellow Fever
Stopper
Neomycin
Afluria (CSL)
Influenza
≤0.2 pg (Neomycin sulfate)
Agriflu (Novartis)
Influenza
≤0.02 mcg
Attenuvax (Merck)
Measles
25 mcg
Dryvax (W)
Smallpox
100 mcg/mL (50 units/0.5 mL)
Fluvirin (Novartis)
Influenza
≤2.5 mcg
H1N1 (CSL)
H1N1 Influenza
≤0.2 pg (Neomycin sulfate)
H1N1 (Novartis)
H1N1 Influenza
≤2.5 mcg
Havrix (GSK)
Hep A
≤40 ng/mL (Neomycin sulfate)
Imovax Rabies (sp)
Rabies
<150 mcg (Neomycin Sulfate)
IPOL (sp)
Polio
<5 ng
Kinrix (GSK)
DTaP/IPV
≤0.05 ng
Meruvax II (Merck)
Rubella
25 mcg
MMR II (Merck)
MMR
25 mcg
Mumpsvax (Merck)
Mumps
25 mcg
Pentacel (sp)
DTaP-IPV-Hib
<4 pg
Pediarix (GSK)
DTaP-HepB-IPV
≤0.05 ng
ProQuad (Merck)
MMR+Varicella
<16 mcg
RabAvert (Chiron)
Rabies
< 1 mcg
Twinrix (GSK)
Hep AB
≤20 ng
Varivax (Merck)
Varicella
trace amounts
Zostavax (Merck)
Varicella Zoster
trace amounts
Ovalbumin
Afluria (CSL)
Influenza
≤ 1 mcg
Fluarix (GSK)
Influenza
≤ 1 mcg
FluLaval (sp) Influenza ≤1 mcg H1N1 (Novartis) H1N1 Influenza ≤1 mcg H1N1 (GSK) H1N1 Influenza ≤1 mcg
RabAvert (Novartis)
Rabies
< 3 ug
Polymyxin B
Afluria (CSL)
Influenza
≤0.03pg
Dryvax (W)
Smallpox
100 units/mL (50 units/0.5 mL)
Fluvirin (Novartis)
Influenza
undetectable amounts
H1N1 (Novartis)
H1N1 Influenza
≤3.75 mcg
IPOL (sp)
Polio
25 ng
Kinrix (GSK)
DTaP/IPV
≤0.01 ng
Pediarix (GSK)
DTaP-HepB-IPV
≤0.01 ng
Pentacel (sp)
DTaP-IPV-Hib
<4 pg (polymyxin B sulfate)
Serum, Fetal Bovine
Attenuvax (Merck)
Measles
<1 ppm
IPOL (sp)
Polio
<1 ppm
Meruvax II (Merck)
Rubella
<1 ppm
MMR II (Merck)
MMR
<1 ppm
Mumpsvax (Merck)
Mumps
<1 ppm
ProQuad (Merck)
MMR+varicella
0.5 mcg
RotaTeq (Merck)
Rotavirus
trace amounts
Varivax (Merck)
Varicella
trace amounts
Zostavax (Merck)
Varicella Zoster
trace amounts
Sodium taurodeoxycholate
Afluria (CSL)
Influenza
<10 ppm
Streptomycin
IPOL (sp)
Polio
<200 ng
Thimerosal Afluria (CSL)
Influenza
24.5 mcg mercury
Decavac (sp)
Td
trace amounts; ≤0.3 mcg mercury
DT (sp)
DT
25 mcg mercury in multidose; trace amounts in single dose
FluLaval (GSK)
Influenza
25 mcg mercury
Fluvirin (Novartis)
Influenza
≤1 mcg mercury in prefilled syringe; 25 mcg mercury per dose in multidose vial
Fluzone (sp)
Influenza
none in No Preservative presentations; 25 mcg mercury in multi-dose vial
H1N1 (CSL)
H1N1 Influenza
24.5 mcg mercury
H1N1 (Novartis)
H1N1 Influenza
≤1 mcg mercury in prefilled syringe; 25 mcg mercury per dose in multidose vial
H1N1 (sp)
H1N1 Influenza
none in No Preservative presentations; 25 mcg mercury in multi-dose vial
JE-Vax (sp)
Japanese Encephalitis
0.007%
MENOMUNE (sp)
Meningococcal
25 mcg mercury in multidose; trace amounts in single dose
Pediarix (GSK)
DtAp-HepB-IPV
trace amounts
Tetanus Toxoid Adsorbed (Aventis)
Tetanus Toxoid Adsorbed
25 mcg mercury in multidose vial; ≤0.3 mcg mercury in single dose
TriHIBit (sp)
Hib
trace amounts
Tripedia (sp)
DTaP
trace amounts; ≤0.3 mcg mercury
Yeast
Comvax (Merck)
Hib-HepB
"The vaccine contains no detectable yeast DNA, and 1% or less of the protein is of yeast origin."
Engerix-B (GSK)
Hep B
<5% yeast protein
Gardasil (Merck) HPV <7 mcg yeast protein/dose HibTITER (Wyeth) Hib "…yeast extract-based medium that is ultrafiltered before use."
Menveo (Novartis)
Meningococcal
"...CY medium containing yeast extracts ..."
Pediarix (GSK)
Hep B
≤5% yeast protein
Prevnar (WL)
Pneumococcal
"…and yeast extract-based medium"
Recombivax HB (Merck)
Hep B
<1%
Twinrix (GSK)
Hep AB
≤5% yeast protein
Vivotif Berna (Berna)
Typhoid
yeast extract from media
updated February 2010
This page was last updated on February 23, 2010
© 2010 Institute for Vaccine Safety
